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Single-model lab wrapper for Bedessem2014 - HiF-1 a -mediated response to hypoxia on the G1/S transition. Cell Cycle Bedessem2014Hif1AMediated Response To Hypoxi Model1812040001Model represents core biological mechanisms from biomodels_ebi reference biomodels_ebi:MODEL1812040001. When you run it, you can inspect state and compare temporal behavior between baseline and adjusted inputs.
Manifest
{
"io": {
"inputs": [],
"outputs": [
{
"name": "model_state_m_m",
"label": "Model state M (m)",
"maps_to": "cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.model_state_m_m",
"description": "Tracks Model state M (m) in the lab model via `cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.model_state_m_m`."
},
{
"name": "cyclin_d",
"label": "Cyclin D",
"maps_to": "cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.cyclin_d",
"description": "Tracks Cyclin D in the lab model via `cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.cyclin_d`."
},
{
"name": "rb_tumor_suppressor",
"label": "Rb tumor suppressor",
"maps_to": "cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.rb_tumor_suppressor",
"description": "Tracks Rb tumor suppressor in the lab model via `cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.rb_tumor_suppressor`."
},
{
"name": "cyclin_e",
"label": "Cyclin E",
"maps_to": "cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.cyclin_e",
"description": "Tracks Cyclin E in the lab model via `cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.cyclin_e`."
},
{
"name": "scf_ubiquitin_ligase",
"label": "SCF ubiquitin ligase",
"maps_to": "cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.scf_ubiquitin_ligase",
"description": "Tracks SCF ubiquitin ligase in the lab model via `cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.scf_ubiquitin_ligase`."
},
{
"name": "e2f_transcription_factor",
"label": "E2F transcription factor",
"maps_to": "cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.e2f_transcription_factor",
"description": "Tracks E2F transcription factor in the lab model via `cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.e2f_transcription_factor`."
},
{
"name": "e2f_a",
"label": "E2F A",
"maps_to": "cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.e2f_a",
"description": "Tracks E2F A in the lab model via `cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.e2f_a`."
},
{
"name": "e2f_rb",
"label": "E2F Rb",
"maps_to": "cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.e2f_rb",
"description": "Tracks E2F Rb in the lab model via `cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.e2f_rb`."
}
]
},
"title": "Bedessem2014 - HiF-1 a -mediated response to hypoxia on the G1/S transition Lab",
"models": [
{
"path": "models/core",
"alias": "cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model_state"
],
"from": "cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.state"
},
{
"to": [
"visualisation.cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model_summary"
],
"from": "cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.summary"
},
{
"to": [
"visualisation.cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model_species_labels"
],
"from": "cellcycle_sbml_bedessem2014_hif_1_a_mediated_response_to_hypoxi_model1812040001_model.species_labels"
}
],
"package": "bedessem2014-hif1a-g1-s-transition",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "Single-model lab wrapper for Bedessem2014 - HiF-1 a -mediated response to hypoxia on the G1/S transition. Cell Cycle Bedessem2014Hif1AMediated Response To Hypoxi Model1812040001Model represents core biological mechanisms from biomodels_ebi reference biomodels_ebi:MODEL1812040001. When you run it, you can inspect state and compare temporal behavior between baseline and adjusted inputs.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagebedessem2014-hif1a-g1-s-transition
Created2026-05-15
Updated2026-06-13
cellcyclesbmlbiomodels_ebifaithfulvisualisationother