Chickarmane2006 Irreversible Stem Cell Switch Lab

{
  "io": {
    "inputs": [
      {
        "name": "p53_signal",
        "label": "p53 signal",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "chickarmane2006_irreversible_switch.p53_signal",
        "description": "Sets the fixed p53 boundary signal used by the stem-cell switch reactions. Maps to SBML symbol `p53`."
      }
    ],
    "outputs": [
      {
        "name": "octamer_binding_transcription_factor_4",
        "label": "OCT4",
        "maps_to": "chickarmane2006_irreversible_switch.octamer_binding_transcription_factor_4",
        "description": "OCT4. Maps to SBML symbol `OCT4`."
      },
      {
        "name": "sry_box_transcription_factor_2",
        "label": "SOX2",
        "maps_to": "chickarmane2006_irreversible_switch.sry_box_transcription_factor_2",
        "description": "SOX2. Maps to SBML symbol `SOX2`."
      },
      {
        "name": "nanog_homeobox",
        "label": "NANOG",
        "maps_to": "chickarmane2006_irreversible_switch.nanog_homeobox",
        "description": "NANOG. Maps to SBML symbol `NANOG`."
      },
      {
        "name": "octamer_binding_transcription_factor_4_sry_box_transcription_factor_2_complex",
        "label": "OCT4-SOX2 complex",
        "maps_to": "chickarmane2006_irreversible_switch.octamer_binding_transcription_factor_4_sry_box_transcription_factor_2_complex",
        "description": "OCT4-SOX2 complex. Maps to SBML symbol `OCT4_SOX2`."
      },
      {
        "name": "differentiation_protein",
        "label": "Differentiation protein",
        "maps_to": "chickarmane2006_irreversible_switch.differentiation_protein",
        "description": "Differentiation protein. Maps to SBML symbol `Protein`."
      },
      {
        "name": "state",
        "maps_to": "chickarmane2006_irreversible_switch.state",
        "description": "Full friendly observable record."
      },
      {
        "name": "summary",
        "maps_to": "chickarmane2006_irreversible_switch.summary",
        "description": "Core model run summary."
      },
      {
        "name": "species_labels",
        "maps_to": "chickarmane2006_irreversible_switch.species_labels",
        "description": "Friendly observable display labels."
      }
    ]
  },
  "title": "Chickarmane2006 Irreversible Stem Cell Switch Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "chickarmane2006_irreversible_switch",
      "parameters": {
        "model_path": "data/BIOMD0000000204.xml",
        "integration_step": 0.1
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.core_state"
      ],
      "from": "chickarmane2006_irreversible_switch.state"
    },
    {
      "to": [
        "visualisation.core_summary"
      ],
      "from": "chickarmane2006_irreversible_switch.summary"
    },
    {
      "to": [
        "visualisation.core_species_labels"
      ],
      "from": "chickarmane2006_irreversible_switch.species_labels"
    }
  ],
  "package": "chickarmane2006-irreversible-stem-cell-switch",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "Irreversible embryonic stem-cell transcriptional switch executed directly from the bundled SBML source.",
  "schema_version": "2.0"
}