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p53 irradiation/cell-fate response. The p53 transcription factor is a regulator of key cellular processes including DNA repair, cell cycle arrest, and apoptosis. In this theoretical study, we investigate how the complex circuitry of the.
Manifest
{
"io": {
"inputs": [],
"outputs": [
{
"name": "dna_double_strand_breaks",
"maps_to": "hat2016_p53_irradiation_response.dna_double_strand_breaks"
},
{
"name": "p53_arrester",
"maps_to": "hat2016_p53_irradiation_response.p53_arrester"
},
{
"name": "p53_killer",
"maps_to": "hat2016_p53_irradiation_response.p53_killer"
},
{
"name": "mdm2_messenger_rna",
"maps_to": "hat2016_p53_irradiation_response.mdm2_messenger_rna"
},
{
"name": "state",
"maps_to": "hat2016_p53_irradiation_response.state"
},
{
"name": "summary",
"maps_to": "hat2016_p53_irradiation_response.summary"
},
{
"name": "species_labels",
"maps_to": "hat2016_p53_irradiation_response.species_labels"
}
]
},
"title": "Hat2016 P53 Irradiation Response Lab",
"models": [
{
"path": "models/core",
"alias": "hat2016_p53_irradiation_response",
"parameters": {
"model_path": "data/BIOMD0000000943.xml",
"integration_step": 0.1
}
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.hat2016_p53_irradiation_response_dna_double_strand_breaks"
],
"from": "hat2016_p53_irradiation_response.dna_double_strand_breaks"
},
{
"to": [
"visualisation.hat2016_p53_irradiation_response_p53_arrester"
],
"from": "hat2016_p53_irradiation_response.p53_arrester"
},
{
"to": [
"visualisation.hat2016_p53_irradiation_response_p53_killer"
],
"from": "hat2016_p53_irradiation_response.p53_killer"
},
{
"to": [
"visualisation.hat2016_p53_irradiation_response_mdm2_messenger_rna"
],
"from": "hat2016_p53_irradiation_response.mdm2_messenger_rna"
},
{
"to": [
"visualisation.hat2016_p53_irradiation_response_state"
],
"from": "hat2016_p53_irradiation_response.state"
},
{
"to": [
"visualisation.hat2016_p53_irradiation_response_summary"
],
"from": "hat2016_p53_irradiation_response.summary"
},
{
"to": [
"visualisation.hat2016_p53_irradiation_response_species_labels"
],
"from": "hat2016_p53_irradiation_response.species_labels"
}
],
"package": "hat2016-p53-irradiation-response",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.1",
"description": "p53 irradiation/cell-fate response. The p53 transcription factor is a regulator of key cellular processes including DNA repair, cell cycle arrest, and apoptosis. In this theoretical study, we investigate how the complex circuitry of the.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagehat2016-p53-irradiation-response
Created2026-05-15
Updated2026-06-13
generegulationsbmlbiomodels_ebifaithfulvisualisationother