Mosca2012 - Central Carbon Metabolism Regulated by AKT Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_glucose",
        "units": "native SBML value",
        "default": 0.000897,
        "maps_to": "metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model.initial_glucose",
        "description": "Initial condition for glucose. Maps to bundled SBML symbol `species_1`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_glucose_6_phosphate",
        "units": "native SBML value",
        "default": 0.00109,
        "maps_to": "metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model.initial_glucose_6_phosphate",
        "description": "Initial condition for glucose 6 phosphate. Maps to bundled SBML symbol `species_2`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_atp",
        "units": "native SBML value",
        "default": 0.0087,
        "maps_to": "metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model.initial_atp",
        "description": "Initial condition for atp. Maps to bundled SBML symbol `species_4`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_fructose_6_phosphate",
        "units": "native SBML value",
        "default": 0.0000362,
        "maps_to": "metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model.initial_fructose_6_phosphate",
        "description": "Initial condition for fructose 6 phosphate. Maps to bundled SBML symbol `species_5`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_fructose_1_6_bisphosphate",
        "units": "native SBML value",
        "default": 0.000367,
        "maps_to": "metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model.initial_fructose_1_6_bisphosphate",
        "description": "Initial condition for fructose 1 6 bisphosphate. Maps to bundled SBML symbol `species_6`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      }
    ],
    "outputs": [
      {
        "name": "glucose",
        "maps_to": "metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model.glucose"
      },
      {
        "name": "glucose_6_phosphate",
        "maps_to": "metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model.glucose_6_phosphate"
      },
      {
        "name": "atp",
        "maps_to": "metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model.atp"
      },
      {
        "name": "fructose_6_phosphate",
        "maps_to": "metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model.fructose_6_phosphate"
      },
      {
        "name": "fructose_1_6_bisphosphate",
        "maps_to": "metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model.fructose_1_6_bisphosphate"
      },
      {
        "name": "observable_values",
        "maps_to": "metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model.observable_values"
      },
      {
        "name": "run_summary",
        "maps_to": "metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model.run_summary"
      },
      {
        "name": "observable_labels",
        "maps_to": "metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model.observable_labels"
      }
    ]
  },
  "title": "Mosca2012 - Central Carbon Metabolism Regulated by AKT Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model",
      "parameters": {
        "model_path": "data/BIOMD0000000426.xml",
        "integration_step": 0.1
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model_observable_values"
      ],
      "from": "metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model.observable_values"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model_run_summary"
      ],
      "from": "metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model.run_summary"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model_observable_labels"
      ],
      "from": "metabolism_sbml_mosca2012_central_carbon_metabolism_regulated_by_biomd0000000426_model.observable_labels"
    }
  ],
  "package": "mosca2012-central-carbon-metabolism-regulated-by-akt",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "Mosca2012 - Central Carbon Metabolism Regulated by AKT The role of the PI3K/Akt/PKB signalling pathway in oncogenesis has been extensively investigated and altered expression or mutations of many comp. It can be used to explore metabolic flux dynamics and compare pathway behavior across conditions.",
  "schema_version": "2.0"
}