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This the model from the article: A biochemically structured model for Saccharomyces cerevisiae. It can be used to explore systemsbiology lei2001 yeast aerobic metabolism BioModels0000000245 dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_glucose_feed",
"label": "Initial Glucose Feed",
"maps_to": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.initial_glucose_feed",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `S_f`."
},
{
"name": "initial_glucose",
"label": "Initial Glucose",
"maps_to": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.initial_glucose",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `s_glu`."
},
{
"name": "initial_red_equ_nadh",
"label": "Initial Red Equ Nadh",
"maps_to": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.initial_red_equ_nadh",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Red`."
},
{
"name": "initial_pyruvate",
"label": "Initial Pyruvate",
"maps_to": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.initial_pyruvate",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `s_pyr`."
},
{
"name": "initial_et_oh",
"label": "Initial Et Oh",
"maps_to": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.initial_et_oh",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `s_EtOH`."
},
{
"name": "initial_bm_ac_dh",
"label": "Initial Bm Ac Dh",
"maps_to": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.initial_bm_ac_dh",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `AcDH`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.species_labels"
},
{
"name": "glucose_feed",
"maps_to": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.glucose_feed"
},
{
"name": "glucose",
"maps_to": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.glucose"
},
{
"name": "red_equ_nadh",
"maps_to": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.red_equ_nadh"
},
{
"name": "pyruvate",
"maps_to": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.pyruvate"
},
{
"name": "et_oh",
"maps_to": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.et_oh"
},
{
"name": "bm_ac_dh",
"maps_to": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.bm_ac_dh"
}
]
},
"tags": [
"metabolism",
"microbiology",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Lei2001 Yeast Aerobic Metabolism Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model_state"
],
"from": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model_summary"
],
"from": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model_species_labels"
],
"from": "systemsbiology_sbml_lei2001_yeast_aerobic_metabolism_biomd0000000245_model.species_labels"
}
],
"package": "lei2001-yeast-aerobic-metabolism",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "This the model from the article: A biochemically structured model for Saccharomyces cerevisiae. It can be used to explore systemsbiology lei2001 yeast aerobic metabolism BioModels0000000245 dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagelei2001-yeast-aerobic-metabolism
Created2026-05-17
Updated2026-06-13
metabolismmicrobiologysystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother