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This ordinary differential equation model of cancer virotherapy dynamics is described in the publication:Salma M. It can be used to explore tumor-related dynamics and compare treatment-response behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_uninfected_cancer_cells",
"label": "Uninfected cancer cells",
"units": "native SBML value",
"default": 0.6,
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_p_biomd0000001031_model.initial_uninfected_cancer_cells",
"description": "Initial Uninfected cancer cells. Sets the initial value of bundled SBML symbol `uninfected_cancer_cells`."
},
{
"name": "initial_infected_cancer_cells",
"label": "Infected cancer cells",
"units": "native SBML value",
"default": 0,
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_p_biomd0000001031_model.initial_infected_cancer_cells",
"description": "Initial Infected cancer cells. Sets the initial value of bundled SBML symbol `infected_cancer_cells`."
},
{
"name": "initial_free_virus",
"label": "Free virus",
"units": "native SBML value",
"default": 0.5,
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_p_biomd0000001031_model.initial_free_virus",
"description": "Initial Free virus. Sets the initial value of bundled SBML symbol `free_virus`."
}
],
"outputs": [
{
"name": "uninfected_cancer_cells",
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_p_biomd0000001031_model.uninfected_cancer_cells",
"description": "Uninfected cancer cells observable. Maps to SBML symbol `uninfected_cancer_cells`."
},
{
"name": "infected_cancer_cells",
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_p_biomd0000001031_model.infected_cancer_cells",
"description": "Infected cancer cells observable. Maps to SBML symbol `infected_cancer_cells`."
},
{
"name": "free_virus",
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_p_biomd0000001031_model.free_virus",
"description": "Free virus observable. Maps to SBML symbol `free_virus`."
},
{
"name": "state",
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_p_biomd0000001031_model.state",
"description": "Full raw SBML observable record for reproducibility and downstream visualisation."
},
{
"name": "summary",
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_p_biomd0000001031_model.summary",
"description": "Change and peak summary across the simulated SBML observables."
},
{
"name": "species_labels",
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_p_biomd0000001031_model.species_labels",
"description": "Mapping from selected raw SBML observable symbols to display labels."
}
]
},
"tags": [
"biomodels_ebi",
"curated",
"drug-response",
"faithful",
"immunotherapy",
"oncology",
"pharmacology",
"physiology",
"sbml",
"systemsbiology",
"tumor-growth",
"virotherapy"
],
"title": "Al-Tuwairqi2020 - Dynamics of cancer virotherapy - Phase I treatment Lab",
"models": [
{
"path": "models/core",
"alias": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_p_biomd0000001031_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_p_biomd0000001031_model_state"
],
"from": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_p_biomd0000001031_model.state"
},
{
"to": [
"visualisation.oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_p_biomd0000001031_model_summary"
],
"from": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_p_biomd0000001031_model.summary"
},
{
"to": [
"visualisation.oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_p_biomd0000001031_model_species_labels"
],
"from": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_p_biomd0000001031_model.species_labels"
}
],
"package": "al-tuwairqi2020-dynamics-of-cancer-virotherapy-phase-i-treatment",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "This ordinary differential equation model of cancer virotherapy dynamics is described in the publication:Salma M. It can be used to explore tumor-related dynamics and compare treatment-response behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packageal-tuwairqi2020-dynamics-of-cancer-virotherapy-phase-i-treatment
Created2026-05-16
Updated2026-06-13
biomodels_ebicurateddrug-responsefaithfulimmunotherapyoncologypharmacologyphysiologysbmlsystemsbiologytumor-growthvirotherapyvisualisationother